2021 Publications

Donate to our Cause


Browse the latest video presentations on topics such as cancer, heart disease, and oxidative stress from Randolph M. Howes, M.D., Ph.D.

View our Videos ›


Download the latest books from The Howes Selective World Library of Oxygen Metabolism. Dr. Howes currently has 11 books in publication.

Browse the Online Store ›


“Cholesterol Myths”

Cholesterol is an essential component of animal cell membranes; as such, it is synthesized by all animal cells. Regardless of its bad name, cholesterol is essential for life. Aside from its structural role in membranes, it is also vital in the production of steroid hormones, vitamin D, and bile acid. So, although high levels are a risk factor for disease, without any cholesterol, we could not survive. The World Health Organization (WHO) estimates that raised cholesterol levels are responsible for 2.6 million deaths each year. Given such prevalence, it is no surprise that misinformation about cholesterol is rife. Cholesterol balance is really a function of what we eat but also our genetics. A person can be born with a genetic tendency to not process cholesterol efficiently. Because it’s genetic it has been called familial hypercholesterolemia, and it might be as common as 1 in 200 people. Even if you have a healthy weight, your cholesterol can be abnormal. Other factors that impact your cholesterol are the foods you eat, your exercise habits, whether you smoke, and how much alcohol you drink. Cholesterol levels are affected by genetics, thyroid function, medications, exercise, sleep, and diet. People who exercise are less likely to see elevations in cholesterol from eating cholesterol compared with sedentary people. High cholesterol leads to silent buildup of plaque in arteries until it is so severe that strokes or heart attacks occur. You don’t go to the store and buy a package of cholesterol, but you do buy red meat, cheeses, and eggs. Red meat contains saturated fat and cholesterol.

Download the complete article (a PDF).yths